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埃替非巴肽(Eptifibatide)

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PRO-358埃替非巴肽(Eptifibatide) 5mg/25mg/100mg Prospec

 

 

Description :
 Synthetic Eptifibatide is a 6 amino acid peptide having a MW of 832 dalton the following sequence Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 .Eptifibatide binds to the plaet receptor glycoprotein(GP) IIb/IIIa of human plaets and inhibits plaet aggregation.

 
Physical Appearance:
 Sterile Filtered White lyophilized (freeze-dried) powder.

 
Formulation:
 Eptifibatide was lyophilized with no additives.

 
Solubility:
 It is recommended to reconstitute the lyophilized Eptifibatide in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

 
Stability:
 
 Lyophilized Eptifibatide although stable at room temperature for 3 weeks, should be stored desiccated below -18 C. Upon reconstitution Eptifibatide should be stored at 4 C between 2-7 days and for future use below -18 C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Please avoid freeze-thaw cycles.

 
Purity:
 Greater than 95.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Anion-exchange FPLC.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.

 
Dimers and aggregates:
 Less than 1% as determined by silver-stained SDS-PAGE gel analysis.

 
Endotoxin:
 Less than 0.1 ng/µg (IEU/µg) of Eptifibatide .

 
Protein content:
 Protein quantitation was carried out by two independent methods:

1. UV spectroscopy at 280 nm
2. Analysis by RP-HPLC, using a standard solution of Eptifibatide as a Reference Standard.

 
Usage:
 Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.


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